
Hyperemesis gravidarum represents the most severe end of the spectrum of pregnancy related nausea and vomiting. Complications can include renal failure, venous thromboembolism, suicidal ideation and termination of a wanted pregnancy. This screencast discusses the diagnostic criteria, which are based on symptoms rather than signs of dehydration. The PUQE score is explained, which can be used to support a diagnosis, and the evidence base behind the safety of antiemetics in the first trimester is reviewed.
An educational grant was received from Pregnancy Sickness Support for the production of this screencast. Editorial and content decisions were made solely by the RCGP.

